LUPUS ERYTHEMATOSUS. Patients with systemic lupus suffer from the destruction of internal organs that is accompanied by a rash on the cheeks and nose. The main symptoms are pain in joints, red spots on the head, face, hands, ears and breasts. Patients also complain of sensitivity to sunlight, fatigue and anxiety. Doctors still do not know the exact reasons of the illness. Presumably, the development of lupus is related to some violations in the immune system functioning.